3geh: Difference between revisions

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<StructureSection load='3geh' size='340' side='right'caption='[[3geh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
<StructureSection load='3geh' size='340' side='right'caption='[[3geh]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3geh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Anabaena_7120 Anabaena 7120]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEH FirstGlance]. <br>
<table><tr><td colspan='2'>[[3geh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3GEH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3GEH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FON:N-{[4-({[(6R)-2-AMINO-5-FORMYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)PHENYL]CARBONYL}-L-GLUTAMIC+ACID'>FON</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1rfl|1rfl]], [[1xzp|1xzp]], [[1xzq|1xzq]], [[2gja|2gja]], [[2gj8|2gj8]], [[2gj9|2gj9]], [[3cp2|3cp2]], [[3cp8|3cp8]], [[3gee|3gee]], [[3gei|3gei]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FON:N-{[4-({[(6R)-2-AMINO-5-FORMYL-4-OXO-1,4,5,6,7,8-HEXAHYDROPTERIDIN-6-YL]METHYL}AMINO)PHENYL]CARBONYL}-L-GLUTAMIC+ACID'>FON</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mnmE, trmE, all4677 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=103690 Anabaena 7120])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3geh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3geh OCA], [https://pdbe.org/3geh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3geh RCSB], [https://www.ebi.ac.uk/pdbsum/3geh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3geh ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3geh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3geh OCA], [https://pdbe.org/3geh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3geh RCSB], [https://www.ebi.ac.uk/pdbsum/3geh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3geh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MNME_NOSS1 MNME_NOSS1]] Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.[HAMAP-Rule:MF_00379]  
[https://www.uniprot.org/uniprot/MNME_NOSS1 MNME_NOSS1] Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.[HAMAP-Rule:MF_00379]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Anabaena 7120]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Meyer, S]]
[[Category: Nostoc sp. PCC 7120 = FACHB-418]]
[[Category: Wittinghofer, A]]
[[Category: Meyer S]]
[[Category: G protein]]
[[Category: Wittinghofer A]]
[[Category: Gtp-binding]]
[[Category: Gtpase]]
[[Category: Hydrolase]]
[[Category: Magnesium]]
[[Category: Metal-binding]]
[[Category: Nucleotide-binding]]
[[Category: Potassium]]
[[Category: Trna modification]]
[[Category: Trna processing]]
[[Category: U34]]
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