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==Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (TIR:1AD)==
==Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (TIR:1AD)==
<StructureSection load='7nak' size='340' side='right'caption='[[7nak]]' scene=''>
<StructureSection load='7nak' size='340' side='right'caption='[[7nak]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NAK FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7NAK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7NAK FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nak OCA], [https://pdbe.org/7nak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nak RCSB], [https://www.ebi.ac.uk/pdbsum/7nak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nak ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1QD:[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl]+[(2~{R},3~{S},4~{R},5~{R})-5-(5-iodanylisoquinolin-2-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl+hydrogen+phosphate'>1QD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7nak FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7nak OCA], [https://pdbe.org/7nak PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7nak RCSB], [https://www.ebi.ac.uk/pdbsum/7nak PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7nak ProSAT]</span></td></tr>
</table>
</table>
==See Also==
*[[SARM1 3D structures|SARM1 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>

Latest revision as of 05:45, 5 June 2024

Cryo-EM structure of activated human SARM1 in complex with NMN and 1AD (TIR:1AD)

7nak, resolution 2.90Å

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