7z9a: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 7z9a is ~~ON HOLD~~

==Sam68==

~~Authors~~: ~~Nadal~~, M., ~~Fuentes~~-~~Prior~~, P.

== Structural highlights ==

<table><tr><td colspan='2'>[[7z9a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z9A OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7Z9A FirstGlance].

~~Description~~: ~~Sam68~~

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>

[[Category: Fuentes-Prior, P]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7z9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z9a OCA], [https://pdbe.org/7z9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z9a RCSB], [https://www.ebi.ac.uk/pdbsum/7z9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z9a ProSAT]</td></tr>

[[Category: Nadal, M]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/KHDR1_HUMAN KHDR1_HUMAN] Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.<ref>PMID:9013542</ref> <ref>PMID:9045636</ref> <ref>PMID:11585385</ref> <ref>PMID:1374686</ref> [UniProtKB:Q60749][UniProtKB:Q8UUW7] Isoform 3, which is expressed in growth-arrested cells only, inhibits S phase.<ref>PMID:9013542</ref> <ref>PMID:9045636</ref> <ref>PMID:11585385</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Fuentes-Prior P]]

[[Category: Nadal M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7z9a is ON HOLD
+==Sam68==
+<StructureSection load='7z9a' size='340' side='right'caption='[[7z9a]], [[Resolution|resolution]] 2.57&Aring;' scene=''>
-Authors: Nadal, M., Fuentes-Prior, P.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7z9a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z9A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z9A FirstGlance]. <br>
-Description: Sam68
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.57&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene></td></tr>
-[[Category: Fuentes-Prior, P]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z9a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z9a OCA], [https://pdbe.org/7z9a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z9a RCSB], [https://www.ebi.ac.uk/pdbsum/7z9a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z9a ProSAT]</span></td></tr>
-[[Category: Nadal, M]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/KHDR1_HUMAN KHDR1_HUMAN] Recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. Role in G2-M progression in the cell cycle. Represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. Also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.<ref>PMID:9013542</ref> <ref>PMID:9045636</ref> <ref>PMID:11585385</ref> <ref>PMID:1374686</ref> [UniProtKB:Q60749][UniProtKB:Q8UUW7]  Isoform 3, which is expressed in growth-arrested cells only, inhibits S phase.<ref>PMID:9013542</ref> <ref>PMID:9045636</ref> <ref>PMID:11585385</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Fuentes-Prior P]]
+[[Category: Nadal M]]