7zho: Difference between revisions
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New page: '''Unreleased structure''' The entry 7zho is ON HOLD Authors: Chaikuad, A., Axtman, A., Knapp, S., Structural Genomics Consortium (SGC) Description: Crystal structure of TTBK1 in compl... |
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==Crystal structure of TTBK1 in complex with compound 3 (7-001)== | |||
<StructureSection load='7zho' size='340' side='right'caption='[[7zho]], [[Resolution|resolution]] 2.08Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7zho]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZHO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZHO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.08Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IQR:4-[3-(2-azanylpyrimidin-4-yl)-1~{H}-indol-5-yl]-2-methyl-but-3-yn-2-ol'>IQR</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zho FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zho OCA], [https://pdbe.org/7zho PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zho RCSB], [https://www.ebi.ac.uk/pdbsum/7zho PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zho ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/TTBK1_HUMAN TTBK1_HUMAN] Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU.<ref>PMID:16923168</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Axtman A]] | |||
[[Category: Chaikuad A]] | |||
[[Category: Knapp S]] | |||
Latest revision as of 08:03, 7 February 2024
Crystal structure of TTBK1 in complex with compound 3 (7-001)
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