7zmu: Difference between revisions
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New page: '''Unreleased structure''' The entry 7zmu is ON HOLD Authors: Description: Category: Unreleased Structures |
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==14-3-3s binding to non-natural peptide 2d== | |||
<StructureSection load='7zmu' size='340' side='right'caption='[[7zmu]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7zmu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZMU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3S:(3R)-3-AMINO-4-HYDROXYBUTANOIC+ACID'>B3S</scene>, <scene name='pdbligand=BAL:BETA-ALANINE'>BAL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PPN:PARA-NITROPHENYLALANINE'>PPN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zmu OCA], [https://pdbe.org/7zmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zmu RCSB], [https://www.ebi.ac.uk/pdbsum/7zmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zmu ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Craenmehr FWB]] | |||
[[Category: Ottmann C]] | |||
[[Category: Somsen BA]] | |||
Latest revision as of 11:22, 15 November 2023
14-3-3s binding to non-natural peptide 2d
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