2yd8: Difference between revisions

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<StructureSection load='2yd8' size='340' side='right'caption='[[2yd8]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='2yd8' size='340' side='right'caption='[[2yd8]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2yd8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YD8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2yd8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YD8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YYJ:1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose'>YYJ</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2yd1|2yd1]], [[2yd2|2yd2]], [[2yd3|2yd3]], [[2yd4|2yd4]], [[2yd5|2yd5]], [[2yd6|2yd6]], [[2yd7|2yd7]], [[2yd9|2yd9]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YYJ:[(2R,3S,4R,5R)-2-oxidanyl-3,4-disulfooxy-5-(sulfooxymethyl)oxolan-2-yl]methyl+hydrogen+sulfate'>YYJ</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yd8 OCA], [https://pdbe.org/2yd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yd8 RCSB], [https://www.ebi.ac.uk/pdbsum/2yd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yd8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yd8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yd8 OCA], [https://pdbe.org/2yd8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yd8 RCSB], [https://www.ebi.ac.uk/pdbsum/2yd8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yd8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN]] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref>  The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref>
[https://www.uniprot.org/uniprot/PTPRF_HUMAN PTPRF_HUMAN] Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase).<ref>PMID:10338209</ref>  The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.<ref>PMID:10338209</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Aricescu AR]]
[[Category: Aricescu, A R]]
[[Category: Coles CH]]
[[Category: Coles, C H]]
[[Category: Flanagan JG]]
[[Category: Flanagan, J G]]
[[Category: Gallagher JT]]
[[Category: Gallagher, J T]]
[[Category: Jones EY]]
[[Category: Jones, E Y]]
[[Category: Lu W]]
[[Category: Lu, W]]
[[Category: Shen Y]]
[[Category: Shen, Y]]
[[Category: Siebold C]]
[[Category: Siebold, C]]
[[Category: Sutton GC]]
[[Category: Sutton, G C]]
[[Category: Tenney AP]]
[[Category: Tenney, A P]]
[[Category: Hydrolase]]
[[Category: Rptpf]]