7mr8: Difference between revisions
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==Crystal structure of the first bromodomain (BD1) of human BRD4 bound to GXH-II-076== | ==Crystal structure of the first bromodomain (BD1) of human BRD4 bound to GXH-II-076== | ||
<StructureSection load='7mr8' size='340' side='right'caption='[[7mr8]]' scene=''> | <StructureSection load='7mr8' size='340' side='right'caption='[[7mr8]], [[Resolution|resolution]] 1.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MR8 FirstGlance]. <br> | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7MR8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7MR8 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mr8 OCA], [https://pdbe.org/7mr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mr8 RCSB], [https://www.ebi.ac.uk/pdbsum/7mr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mr8 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZNJ:N-{3-[(2-{3-fluoro-4-[(piperidin-4-yl)carbamoyl]anilino}-5-methylpyrimidin-4-yl)amino]-5-[(2-methylpropane-2-sulfonyl)amino]benzoyl}-L-glutamic+acid'>ZNJ</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7mr8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7mr8 OCA], [https://pdbe.org/7mr8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7mr8 RCSB], [https://www.ebi.ac.uk/pdbsum/7mr8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7mr8 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
==See Also== | |||
*[[Bromodomain-containing protein 3D structures|Bromodomain-containing protein 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Latest revision as of 20:43, 29 July 2026
Crystal structure of the first bromodomain (BD1) of human BRD4 bound to GXH-II-076
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