3p3i: Difference between revisions

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<StructureSection load='3p3i' size='340' side='right'caption='[[3p3i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='3p3i' size='340' side='right'caption='[[3p3i]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3p3i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/"streptomyces_cattleya"_kahan_et_al._1979 "streptomyces cattleya" kahan et al. 1979]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P3I FirstGlance]. <br>
<table><tr><td colspan='2'>[[3p3i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_cattleya Streptomyces cattleya]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P3I FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FAH:FLUOROACETIC+ACID'>FAH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3p2q|3p2q]], [[3p2r|3p2r]], [[3p2s|3p2s]], [[3p3f|3p3f]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=FAH:FLUOROACETIC+ACID'>FAH</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">flK ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=29303 "Streptomyces cattleya" Kahan et al. 1979])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3i OCA], [https://pdbe.org/3p3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p3i RCSB], [https://www.ebi.ac.uk/pdbsum/3p3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3i ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p3i OCA], [https://pdbe.org/3p3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p3i RCSB], [https://www.ebi.ac.uk/pdbsum/3p3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p3i ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FLK_STRCT FLK_STRCT]] Hydrolyzes fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance. Can not use acetyl-CoA as substrate.<ref>PMID:16720268</ref> <ref>PMID:20836570</ref>
[https://www.uniprot.org/uniprot/FLK_STRCT FLK_STRCT] Hydrolyzes fluoroacetyl-CoA before it can react with citrate synthase, and thus confers fluoroacetate resistance. Can not use acetyl-CoA as substrate.<ref>PMID:16720268</ref> <ref>PMID:20836570</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Streptomyces cattleya kahan et al. 1979]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chang, M C.Y]]
[[Category: Streptomyces cattleya]]
[[Category: Coyle, S M]]
[[Category: Chang MCY]]
[[Category: Doudna, J A]]
[[Category: Coyle SM]]
[[Category: Jinek, M]]
[[Category: Doudna JA]]
[[Category: Weeks, A M]]
[[Category: Jinek M]]
[[Category: Hot dog-fold]]
[[Category: Weeks AM]]
[[Category: Hydrolase]]
[[Category: Thioesterase]]
Retrieved from "https://proteopedia.org/3p3i"