8d44: Difference between revisions

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'''Unreleased structure'''


The entry 8d44 is ON HOLD
==Cryo-electron microscopy structure of human kidney Fructose-bisphosphate aldolase B==
 
<StructureSection load='8d44' size='340' side='right'caption='[[8d44]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
Authors: Lyu, M., Yu, E.W.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8d44]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D44 FirstGlance]. <br>
Description: Cryo-electron microscopy structure of human kidney Fructose-bisphosphate aldolase B
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d44 OCA], [https://pdbe.org/8d44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d44 RCSB], [https://www.ebi.ac.uk/pdbsum/8d44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d44 ProSAT]</span></td></tr>
[[Category: Yu, E.W]]
</table>
[[Category: Lyu, M]]
== Disease ==
[https://www.uniprot.org/uniprot/ALDOB_HUMAN ALDOB_HUMAN] Defects in ALDOB are the cause of hereditary fructose intolerance (HFI) [MIM:[https://omim.org/entry/229600 229600]. HFI is an autosomal recessive disease that results in an inability to metabolize fructose and related sugars. Complete exclusion of fructose results in dramatic recovery; however, if not treated properly, HFI subjects suffer episodes of hypoglycemia, general ill condition, and risk of death the remainder of life.<ref>PMID:10970798</ref> <ref>PMID:3383242</ref> <ref>PMID:1967768</ref> <ref>PMID:8299883</ref> <ref>PMID:8162030</ref> <ref>PMID:2336380</ref> <ref>PMID:10024431</ref> <ref>PMID:12205126</ref> <ref>PMID:15532022</ref> <ref>PMID:15880727</ref>
== Function ==
[https://www.uniprot.org/uniprot/ALDOB_HUMAN ALDOB_HUMAN]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Lyu M]]
[[Category: Yu EW]]
Retrieved from "https://proteopedia.org/8d44"