3qbr: Difference between revisions

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<StructureSection load='3qbr' size='340' side='right'caption='[[3qbr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3qbr' size='340' side='right'caption='[[3qbr]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qbr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBR FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qbr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Schistosoma_japonicum Schistosoma japonicum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QBR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QBR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.601&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbr OCA], [https://pdbe.org/3qbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbr RCSB], [https://www.ebi.ac.uk/pdbsum/3qbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qbr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qbr OCA], [https://pdbe.org/3qbr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qbr RCSB], [https://www.ebi.ac.uk/pdbsum/3qbr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qbr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/BAK_HUMAN BAK_HUMAN]] In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis.<ref>PMID:8521816</ref> <ref>PMID:17157251</ref> 
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Blood fluke]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Clarke, O B]]
[[Category: Schistosoma japonicum]]
[[Category: Colman, P M]]
[[Category: Clarke OB]]
[[Category: Evangelista, M]]
[[Category: Colman PM]]
[[Category: Fairlie, W D]]
[[Category: Evangelista M]]
[[Category: Feng, Z]]
[[Category: Fairlie WD]]
[[Category: Kalinna, B]]
[[Category: Feng Z]]
[[Category: Lee, E F]]
[[Category: Kalinna B]]
[[Category: Speed, T P]]
[[Category: Lee EF]]
[[Category: Strasser, A]]
[[Category: Speed TP]]
[[Category: Tchoubrieva, E]]
[[Category: Strasser A]]
[[Category: Apoptosis]]
[[Category: Tchoubrieva E]]
[[Category: Bcl-2-like fold]]
[[Category: Helical bundle]]
Retrieved from "https://proteopedia.org/3qbr"