8d5v: Difference between revisions
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==WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera== | |||
<StructureSection load='8d5v' size='340' side='right'caption='[[8d5v]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8d5v]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] and [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D5V FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d5v OCA], [https://pdbe.org/8d5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d5v RCSB], [https://www.ebi.ac.uk/pdbsum/8d5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d5v ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SIGA_MYCTU SIGA_MYCTU] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth (Probable).<ref>PMID:12354223</ref> <ref>PMID:20729364</ref> <ref>PMID:22570422</ref> [https://www.uniprot.org/uniprot/RPOB_MYCTU RPOB_MYCTU] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Wan T]] | |||
[[Category: Zhang LM]] | |||
Latest revision as of 09:00, 4 June 2025
WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera
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