8dkd: Difference between revisions
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==Sliding clamp from M. thermoresistibile== | |||
<StructureSection load='8dkd' size='340' side='right'caption='[[8dkd]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8dkd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_thermoresistibile_ATCC_19527 Mycolicibacterium thermoresistibile ATCC 19527]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DKD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dkd OCA], [https://pdbe.org/8dkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dkd RCSB], [https://www.ebi.ac.uk/pdbsum/8dkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dkd ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/G7CIP4_MYCT3 G7CIP4_MYCT3] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] | ||
[[Category: Kapur | __TOC__ | ||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycolicibacterium thermoresistibile ATCC 19527]] | |||
[[Category: Gray OJ]] | |||
[[Category: Honzatko RH]] | |||
[[Category: Kapur MK]] | |||
[[Category: Nelson SN]] | |||
Latest revision as of 10:10, 25 October 2023
Sliding clamp from M. thermoresistibile
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