7yjk: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 7yjk is ~~ON HOLD~~

==Cryo-EM structure of the dimeric atSPT-ORM1 complex==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[7yjk]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YJK OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=7YJK FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=Z1T:N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide'>Z1T</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=7yjk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yjk OCA], [https://pdbe.org/7yjk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yjk RCSB], [https://www.ebi.ac.uk/pdbsum/7yjk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yjk ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/SPTC1_ARATH SPTC1_ARATH] Component of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine. The heterodimer formed with LCB2 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis.<ref>PMID:17194770</ref> <ref>PMID:18059378</ref> <ref>PMID:18218968</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Arabidopsis thaliana]]

[[Category: Large Structures]]

[[Category: Gong X]]

[[Category: Liu P]]

[[Category: Xie T]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 7yjk is ON HOLD
+==Cryo-EM structure of the dimeric atSPT-ORM1 complex==
+<StructureSection load='7yjk' size='340' side='right'caption='[[7yjk]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[7yjk]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YJK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YJK FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=Z1T:N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]tetracosanamide'>Z1T</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yjk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yjk OCA], [https://pdbe.org/7yjk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yjk RCSB], [https://www.ebi.ac.uk/pdbsum/7yjk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yjk ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SPTC1_ARATH SPTC1_ARATH] Component of serine palmitoyltransferase (SPT), which catalyzes the committed step in the synthesis of sphingolipids, the condensation of serine with palmitoyl CoA to form the long chain base 3-ketosphinganine. The heterodimer formed with LCB2 constitutes the catalytic core. Involved in the regulation of the programmed cell death (PCD) signaling pathway. Plays an important role during male gametogenesis and embryogenesis.<ref>PMID:17194770</ref> <ref>PMID:18059378</ref> <ref>PMID:18218968</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arabidopsis thaliana]]
+[[Category: Large Structures]]
+[[Category: Gong X]]
+[[Category: Liu P]]
+[[Category: Xie T]]