8dr3: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 8dr3 is ~~ON HOLD~~

==Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD==

== Structural highlights ==

<table><tr><td colspan='2'>[[8dr3]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DR3 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=8DR3 FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=8dr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dr3 OCA], [https://pdbe.org/8dr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dr3 RCSB], [https://www.ebi.ac.uk/pdbsum/8dr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dr3 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/RFC1_YEAST RFC1_YEAST] Component of the ATP-dependent clamp loader RFC complex for the POL30/PCNA homotrimer DNA clamp. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Replication factor C (RFC or activator 1) complex acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment.

~~Authors: Schrecker, M., Hite, R.K.~~

==See Also==

*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]

~~Description: Closed state of RFC:PCNA bound to a 3'' ss~~/~~dsDNA junction (DNA2) with NTD~~

__TOC__

[[Category: ~~Unreleased~~ Structures]]

</StructureSection>

[[Category: Hite~~, R.K~~]]

[[Category: Large Structures]]

[[Category: Schrecker, M]]

[[Category: Saccharomyces cerevisiae]]

[[Category: Hite RK]]

[[Category: Schrecker M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 8dr3 is ON HOLD
+==Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD==
+<StructureSection load='8dr3' size='340' side='right'caption='[[8dr3]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[8dr3]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DR3 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dr3 OCA], [https://pdbe.org/8dr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dr3 RCSB], [https://www.ebi.ac.uk/pdbsum/8dr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dr3 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RFC1_YEAST RFC1_YEAST] Component of the ATP-dependent clamp loader RFC complex for the POL30/PCNA homotrimer DNA clamp. During a clamp loading circle, the RFC:clamp complex binds to DNA and the recognition of the double-stranded/single-stranded junction stimulates ATP hydrolysis by RFC. The complex presumably provides bipartite ATP sites in which one subunit supplies a catalytic site for hydrolysis of ATP bound to the neighboring subunit. Dissociation of RFC from the clamp leaves the clamp encircling DNA. Replication factor C (RFC or activator 1) complex acts during elongation of primed DNA templates by DNA polymerase delta and epsilon. RFC has an essential but redundant activity in sister chromatid cohesion establishment.
-Authors: Schrecker, M., Hite, R.K.
+==See Also==
+*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
-Description: Closed state of RFC:PCNA bound to a 3'' ss/dsDNA junction (DNA2) with NTD
+__TOC__
-[[Category: Unreleased Structures]]
+</StructureSection>
-[[Category: Hite, R.K]]
+[[Category: Large Structures]]
-[[Category: Schrecker, M]]
+[[Category: Saccharomyces cerevisiae]]
+[[Category: Hite RK]]
+[[Category: Schrecker M]]