3vdj: Difference between revisions
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<StructureSection load='3vdj' size='340' side='right'caption='[[3vdj]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3vdj' size='340' side='right'caption='[[3vdj]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3vdj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDJ FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.698Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [https://pdbe.org/3vdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [https://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdj OCA], [https://pdbe.org/3vdj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdj RCSB], [https://www.ebi.ac.uk/pdbsum/3vdj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdj ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CSP_PLAF7 CSP_PLAF7] Essential sporozoite protein (PubMed:29554084, PubMed:32150583). In the mosquito vector, required for sporozoite development in the oocyst, migration through the vector hemolymph and entry into the vector salivary glands (By similarity). In the vertebrate host, required for sporozoite migration through the host dermis and infection of host hepatocytes (PubMed:29554084, PubMed:32150583). Binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes (By similarity).[UniProtKB:P23093]<ref>PMID:29554084</ref> <ref>PMID:32150583</ref> In the vertebrate host, binds to highly sulfated heparan sulfate proteoglycans (HSPGs) on the surface of host hepatocytes and is required for sporozoite invasion of the host hepatocytes.[UniProtKB:P23093] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Plasmodium falciparum 3D7]] | ||
[[Category: Doud | [[Category: Doud MB]] | ||
[[Category: Koksal | [[Category: Koksal AC]] | ||
[[Category: Lu | [[Category: Lu C]] | ||
[[Category: Mi | [[Category: Mi LZ]] | ||
[[Category: Song | [[Category: Song G]] | ||
[[Category: Springer | [[Category: Springer TA]] | ||
