8dt6: Difference between revisions
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New page: '''Unreleased structure''' The entry 8dt6 is ON HOLD Authors: Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCI... |
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The | ==Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis== | ||
<StructureSection load='8dt6' size='340' side='right'caption='[[8dt6]], [[Resolution|resolution]] 2.35Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8dt6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Elizabethkingia_anophelis_NUHP1 Elizabethkingia anophelis NUHP1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DT6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DT6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dt6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dt6 OCA], [https://pdbe.org/8dt6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dt6 RCSB], [https://www.ebi.ac.uk/pdbsum/8dt6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dt6 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A077EHW1_9FLAO A0A077EHW1_9FLAO] Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.[PIRNR:PIRNR000804] | |||
==See Also== | |||
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Elizabethkingia anophelis NUHP1]] | ||
[[Category: Large Structures]] | |||
[[Category: Structural genomic]] | |||
Latest revision as of 09:41, 14 February 2024
Crystal Structure of DNA Polymerase III beta subunit from Elizabethkingia anophelis
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