8e06: Difference between revisions
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The entry | ==Symmetry expansion of dimeric LRRK1== | ||
<StructureSection load='8e06' size='340' side='right'caption='[[8e06]], [[Resolution|resolution]] 4.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8e06]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8E06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8E06 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8e06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8e06 OCA], [https://pdbe.org/8e06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8e06 RCSB], [https://www.ebi.ac.uk/pdbsum/8e06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8e06 ProSAT]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/LRRK1_HUMAN LRRK1_HUMAN] Osteosclerotic metaphyseal dysplasia. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LRRK1_HUMAN LRRK1_HUMAN] Plays a role in the negative regulation of bone mass, acting through the maturation of osteoclasts.[UniProtKB:Q3UHC2] | |||
==See Also== | |||
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]] | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Leschziner AE]] | |||
[[Category: Lin YX]] | |||
[[Category: Reimer JM]] | |||
Latest revision as of 17:44, 1 November 2023
Symmetry expansion of dimeric LRRK1
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