3znp: Difference between revisions
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<StructureSection load='3znp' size='340' side='right'caption='[[3znp]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='3znp' size='340' side='right'caption='[[3znp]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3znp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[3znp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZNP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZNP FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SE2:3-HYDROXY-2H-CHROMEN-2-ONE'>SE2</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3znp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3znp OCA], [https://pdbe.org/3znp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3znp RCSB], [https://www.ebi.ac.uk/pdbsum/3znp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3znp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3znp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3znp OCA], [https://pdbe.org/3znp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3znp RCSB], [https://www.ebi.ac.uk/pdbsum/3znp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3znp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/OXDA_HUMAN OXDA_HUMAN] Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.<ref>PMID:17303072</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Allen | [[Category: Allen MS]] | ||
[[Category: Bowen | [[Category: Bowen CA]] | ||
[[Category: Chytil | [[Category: Chytil M]] | ||
[[Category: Fang | [[Category: Fang QK]] | ||
[[Category: Foglesong | [[Category: Foglesong RJ]] | ||
[[Category: Hardy | [[Category: Hardy LW]] | ||
[[Category: Heffernan | [[Category: Heffernan MLR]] | ||
[[Category: Hopkins | [[Category: Hopkins SC]] | ||
[[Category: Jones | [[Category: Jones SW]] | ||
[[Category: Koch | [[Category: Koch P]] | ||
[[Category: Large | [[Category: Large TH]] | ||
[[Category: Melnick | [[Category: Melnick L]] | ||
[[Category: Molla | [[Category: Molla G]] | ||
[[Category: Nardini | [[Category: Nardini M]] | ||
[[Category: Oliet | [[Category: Oliet SHR]] | ||
[[Category: Orsini | [[Category: Orsini MA]] | ||
[[Category: Panatier | [[Category: Panatier A]] | ||
[[Category: Piubelli | [[Category: Piubelli L]] | ||
[[Category: Pollegioni | [[Category: Pollegioni L]] | ||
[[Category: Saraswat | [[Category: Saraswat LD]] | ||
[[Category: Soukri | [[Category: Soukri M]] | ||
[[Category: Spear | [[Category: Spear KL]] | ||
[[Category: Varney | [[Category: Varney MA]] | ||