3wg6: Difference between revisions

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<StructureSection load='3wg6' size='340' side='right'caption='[[3wg6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3wg6' size='340' side='right'caption='[[3wg6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wg6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WG6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wg6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_parapsilosis Candida parapsilosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WG6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WG6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg6 OCA], [https://pdbe.org/3wg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wg6 RCSB], [https://www.ebi.ac.uk/pdbsum/3wg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wg6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wg6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wg6 OCA], [https://pdbe.org/3wg6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wg6 RCSB], [https://www.ebi.ac.uk/pdbsum/3wg6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wg6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CPRC1_CANPA CPRC1_CANPA] NADPH-dependent conjugated polyketone reductase with broad substrate specificity and strict stereospecificity. Reduces ketopantoyl lactone (2-dehydropantolactone) and isatin. Does not act on menadione, p-nitrobenzaldehyde and pyridine-3-aldehyde.<ref>PMID:11826979</ref> <ref>PMID:14593510</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Candida parapsilosis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Kataoka, M]]
[[Category: Kataoka M]]
[[Category: Maruoka, S]]
[[Category: Maruoka S]]
[[Category: Miyakawa, T]]
[[Category: Miyakawa T]]
[[Category: Nagata, K]]
[[Category: Nagata K]]
[[Category: Ohtsuka, J]]
[[Category: Ohtsuka J]]
[[Category: Qin, H M]]
[[Category: Qin H-M]]
[[Category: Shimizu, S]]
[[Category: Shimizu S]]
[[Category: Tanokura, M]]
[[Category: Tanokura M]]
[[Category: Yamamura, A]]
[[Category: Yamamura A]]
[[Category: Akr superfamily]]
[[Category: D-pantoyl lactone]]
[[Category: Oxidoreductase]]
[[Category: Tim barrel]]

Latest revision as of 19:21, 29 May 2024

Crystal structure of conjugated polyketone reductase C1 from Candida parapsilosis complexed with NADPH

3wg6, resolution 2.20Å

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