3wy9: Difference between revisions

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<StructureSection load='3wy9' size='340' side='right'caption='[[3wy9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='3wy9' size='340' side='right'caption='[[3wy9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3wy9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WY9 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3wy9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WY9 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3wya|3wya]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wy9 OCA], [https://pdbe.org/3wy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wy9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wy9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wy9 OCA], [https://pdbe.org/3wy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wy9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wy9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EF1A_PYRHO EF1A_PYRHO]] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118] [[https://www.uniprot.org/uniprot/RL12_PYRHO RL12_PYRHO]] Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. The stalk complex of P.horikoshii binds to E.coli large subunits and confers on them the ability to interact with eukaryotic elongation factors. Each succesive L12 dimer bound along the P0 spine increases the GTPase activity of elongation factors and increases translation by reconsituted ribosomes.<ref>PMID:17804412</ref> 
[https://www.uniprot.org/uniprot/EF1A_PYRHO EF1A_PYRHO] This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.[HAMAP-Rule:MF_00118]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Honda, T]]
[[Category: Pyrococcus horikoshii OT3]]
[[Category: Ito, K]]
[[Category: Honda T]]
[[Category: Miyoshi, T]]
[[Category: Ito K]]
[[Category: Murakami, R]]
[[Category: Miyoshi T]]
[[Category: Suzuki, T]]
[[Category: Murakami R]]
[[Category: Uchiumi, T]]
[[Category: Suzuki T]]
[[Category: Yao, M]]
[[Category: Uchiumi T]]
[[Category: Aminoacyl-trna]]
[[Category: Yao M]]
[[Category: Aminoacyl-trna delivery]]
[[Category: Gtp]]
[[Category: Gtpase]]
[[Category: Multi-domain]]
[[Category: Stalk protein]]
[[Category: Translation-ribosomal protein complex]]
Retrieved from "https://proteopedia.org/3wy9"