7r6g: Difference between revisions
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<StructureSection load='7r6g' size='340' side='right'caption='[[7r6g]], [[Resolution|resolution]] 2.61Å' scene=''> | <StructureSection load='7r6g' size='340' side='right'caption='[[7r6g]], [[Resolution|resolution]] 2.61Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7r6g]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R6G FirstGlance]. <br> | <table><tr><td colspan='2'>[[7r6g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7R6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7R6G FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TOP:TRIMETHOPRIM'>TOP</scene | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TOP:TRIMETHOPRIM'>TOP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r6g OCA], [https://pdbe.org/7r6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r6g RCSB], [https://www.ebi.ac.uk/pdbsum/7r6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r6g ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7r6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7r6g OCA], [https://pdbe.org/7r6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7r6g RCSB], [https://www.ebi.ac.uk/pdbsum/7r6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7r6g ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DYR5_ECOLX DYR5_ECOLX] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity). | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Escherichia coli]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Erlandsen | [[Category: Erlandsen H]] | ||
[[Category: Estrada | [[Category: Estrada A]] | ||
[[Category: Krucinska | [[Category: Krucinska J]] | ||
[[Category: Wright | [[Category: Wright D]] | ||
Latest revision as of 16:26, 18 October 2023
Crystal structure of DfrA5 dihydrofolate reductase in complex with TRIMETHOPRIM and NADPH
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