8ef8: Difference between revisions
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New page: '''Unreleased structure''' The entry 8ef8 is ON HOLD Authors: Lee, R.E., Griffith, E.C. Description: Staphylococcus aureus ClpP Y63W in complex with compound 3471 [[Category: Unrelease... |
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==Staphylococcus aureus ClpP Y63W in complex with compound 3471== | |||
<StructureSection load='8ef8' size='340' side='right'caption='[[8ef8]], [[Resolution|resolution]] 2.17Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ef8]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_NCTC_8325 Staphylococcus aureus subsp. aureus NCTC 8325]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EF8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=USU:(5S,6S,9aS)-N-[(4-fluorophenyl)methyl]-6-methyl-8-[(naphthalen-1-yl)methyl]-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide'>USU</scene></td></tr> | ||
[[Category: Griffith | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ef8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ef8 OCA], [https://pdbe.org/8ef8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ef8 RCSB], [https://www.ebi.ac.uk/pdbsum/8ef8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ef8 ProSAT]</span></td></tr> | ||
[[Category: Lee | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/CLPP_STAA8 CLPP_STAA8] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Staphylococcus aureus subsp. aureus NCTC 8325]] | |||
[[Category: Griffith EC]] | |||
[[Category: Lee RE]] | |||
Latest revision as of 06:12, 19 July 2023
Staphylococcus aureus ClpP Y63W in complex with compound 3471
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