8b4e: Difference between revisions

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New page: '''Unreleased structure''' The entry 8b4e is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 8b4e is ON HOLD
==ToxR bacterial transcriptional regulator bound to 25 bp toxT promoter DNA==
<StructureSection load='8b4e' size='340' side='right'caption='[[8b4e]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[8b4e]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B4E FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b4e OCA], [https://pdbe.org/8b4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b4e RCSB], [https://www.ebi.ac.uk/pdbsum/8b4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b4e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TOXR_VIBCH TOXR_VIBCH] This transcription activator controls cholera toxin, pilus colonization factor and outer membrane protein expression in V.cholerae. It binds to the 5'-TTTTGAT-3' tandemly repeated DNA sequence in the cholera toxin promoter region. ToxS interacts with the C-terminal periplasmic domain of ToxR, stimulating its activity. It activates transcription at the promoters for tcpI and tcpA and this is presumably via ToxT.


Authors:  
==See Also==
 
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
Description:  
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Vibrio cholerae]]
[[Category: Canals A]]
[[Category: Coll M]]
[[Category: El Yaman N]]
[[Category: Fabrega-Ferrer M]]
[[Category: Krukonis ES]]
[[Category: Muriel M]]
[[Category: Perez-Luque R]]
[[Category: Pieretti S]]
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