8bb8: Difference between revisions
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New page: '''Unreleased structure''' The entry 8bb8 is ON HOLD Authors: Schwartz, M., Neiers, F. Description: Crystal structure of human aldehyde dehydrogenase ALDH3A1 in complex with octanal [[... |
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==Crystal structure of human aldehyde dehydrogenase ALDH3A1 in complex with octanal== | |||
<StructureSection load='8bb8' size='340' side='right'caption='[[8bb8]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8bb8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8BB8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8BB8 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=OYA:OCTANAL'>OYA</scene></td></tr> | ||
[[Category: Neiers | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8bb8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8bb8 OCA], [https://pdbe.org/8bb8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8bb8 RCSB], [https://www.ebi.ac.uk/pdbsum/8bb8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8bb8 ProSAT]</span></td></tr> | ||
[[Category: Schwartz | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Neiers F]] | |||
[[Category: Schwartz M]] | |||
Latest revision as of 08:17, 7 February 2024
Crystal structure of human aldehyde dehydrogenase ALDH3A1 in complex with octanal
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