8dfi: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8dfi]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DFI FirstGlance]. <br> | <table><tr><td colspan='2'>[[8dfi]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DFI FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dfi OCA], [https://pdbe.org/8dfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dfi RCSB], [https://www.ebi.ac.uk/pdbsum/8dfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dfi ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dfi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dfi OCA], [https://pdbe.org/8dfi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dfi RCSB], [https://www.ebi.ac.uk/pdbsum/8dfi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dfi ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ | [https://www.uniprot.org/uniprot/MSP1_PLAF7 MSP1_PLAF7] During the asexual blood stage, involved in merozoite egress from host erythrocytes possibly via its interaction with the host cytoskeleton protein spectrin resulting in the destabilization of the host cytoskeleton and thus leading to erythrocyte cell membrane rupture (PubMed:26468747). Involved in the binding to host erythrocytes and is required for host erythrocyte invasion (PubMed:12692305, PubMed:21175202, PubMed:25778531, PubMed:36202833).<ref>PMID:12692305</ref> <ref>PMID:21175202</ref> <ref>PMID:25778531</ref> <ref>PMID:26468747</ref> <ref>PMID:36202833</ref> By binding to host proinflammatory cytokine S100P may interfere with host immune responses.<ref>PMID:22431641</ref> Involved in merozoite invasion of host erythrocytes (PubMed:1694225, PubMed:29511044). May play a role in the biogenesis and/or function of the food vacuole during the intraerythrocytic development (Probable).<ref>PMID:1694225</ref> <ref>PMID:29511044</ref> <ref>PMID:18769730</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</div> | </div> | ||
<div class="pdbe-citations 8dfi" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 8dfi" style="background-color:#fffaf0;"></div> | ||
==See Also== | |||
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | |||
== References == | == References == | ||
<references/> | <references/> | ||
