8et0: Difference between revisions
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New page: '''Unreleased structure''' The entry 8et0 is ON HOLD until 2024-10-15 Authors: Xu, S., Banerjee, S., Uddin, M.J., Goodman, M.C., Marnett, L.J. Description: Crystal Complex of murine Cy... |
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==Crystal Complex of murine Cyclooxygenase-2 with alpaca nanobody F9== | |||
<StructureSection load='8et0' size='340' side='right'caption='[[8et0]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8et0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus] and [https://en.wikipedia.org/wiki/Vicugna_pacos Vicugna pacos]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ET0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ET0 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IBP:IBUPROFEN'>IBP</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8et0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8et0 OCA], [https://pdbe.org/8et0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8et0 RCSB], [https://www.ebi.ac.uk/pdbsum/8et0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8et0 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Banerjee | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/PGH2_MOUSE PGH2_MOUSE] Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.<ref>PMID:12925531</ref> <ref>PMID:20463020</ref> <ref>PMID:20810665</ref> <ref>PMID:21489986</ref> | ||
[[Category: Marnett | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Vicugna pacos]] | |||
[[Category: Banerjee S]] | |||
[[Category: Goodman MC]] | |||
[[Category: Marnett LJ]] | |||
[[Category: Uddin MJ]] | |||
[[Category: Xu S]] | |||