8exe: Difference between revisions
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New page: '''Unreleased structure''' The entry 8exe is ON HOLD until 2024-10-25 Authors: Description: Category: Unreleased Structures |
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==Crystal structure of human FAM46A-BCCIPa complex at 3.5 angstrom resolution== | |||
<StructureSection load='8exe' size='340' side='right'caption='[[8exe]], [[Resolution|resolution]] 3.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8exe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EXE FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8exe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8exe OCA], [https://pdbe.org/8exe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8exe RCSB], [https://www.ebi.ac.uk/pdbsum/8exe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8exe ProSAT]</span></td></tr> | ||
</table> | |||
== Disease == | |||
[https://www.uniprot.org/uniprot/TET5A_HUMAN TET5A_HUMAN] Osteogenesis imperfecta type 3. The disease is caused by variants affecting the gene represented in this entry. | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TET5A_HUMAN TET5A_HUMAN] Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation (PubMed:33882302). Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs (By similarity).[UniProtKB:D3Z5S8]<ref>PMID:33882302</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu S]] | |||
[[Category: Zhang X]] | |||
Latest revision as of 10:25, 25 October 2023
Crystal structure of human FAM46A-BCCIPa complex at 3.5 angstrom resolution
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