8ey1: Difference between revisions
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New page: '''Unreleased structure''' The entry 8ey1 is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Structure of Arabidopsis fatty acid amide hydrolase mutant S305A in complex with N-(3-oxododecanoyl)-L-homoserine lactone== | |||
<StructureSection load='8ey1' size='340' side='right'caption='[[8ey1]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8ey1]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EY1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EY1 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OHN:N-3-OXO-DODECANOYL-L-HOMOSERINE+LACTONE'>OHN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ey1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ey1 OCA], [https://pdbe.org/8ey1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ey1 RCSB], [https://www.ebi.ac.uk/pdbsum/8ey1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ey1 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FAAH_ARATH FAAH_ARATH] Degrades bioactive fatty acid amides to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Converts N-actylethanolamine (NAE) to ethanolamine. Can also use oleamide or 2-arachidonylglycerol as substrates, but not indole-3-acetamide, 1-naphtalene-acetamide, nicotinic acid amide or L-asparagine. Might be involved in abscisic acid signaling and plant defense through distinctly different mechanisms not involving the catalytic activity.<ref>PMID:12824167</ref> <ref>PMID:16880402</ref> <ref>PMID:18643971</ref> <ref>PMID:19801664</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Aziz M]] | |||
[[Category: Chapman KD]] | |||
[[Category: Gaguancela OA]] | |||
[[Category: Wang X]] | |||
