8b7b: Difference between revisions
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New page: '''Unreleased structure''' The entry 8b7b is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures |
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==Tubulin - maytansinoid - 6 complex== | |||
<StructureSection load='8b7b' size='340' side='right'caption='[[8b7b]], [[Resolution|resolution]] 2.25Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8b7b]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B7B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B7B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACP:PHOSPHOMETHYLPHOSPHONIC+ACID+ADENYLATE+ESTER'>ACP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PX0:(~{Z})-11-[[(1~{R},2~{R},3~{S},5~{S},6~{S},16~{E},18~{E},20~{R},21~{S})-11-chloranyl-12,20-dimethoxy-2,5,9,16-tetramethyl-21-oxidanyl-8,23-bis(oxidanylidene)-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1^{10,14}.0^{3,5}]hexacosa-10(26),11,13,16,18-pentaen-6-yl]oxy]-11-oxidanylidene-undec-2-enoic+acid'>PX0</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b7b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b7b OCA], [https://pdbe.org/8b7b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b7b RCSB], [https://www.ebi.ac.uk/pdbsum/8b7b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b7b ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TBA1B_BOVIN TBA1B_BOVIN] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. | |||
==See Also== | |||
*[[Stathmin-4 3D structures|Stathmin-4 3D structures]] | |||
*[[Tubulin 3D Structures|Tubulin 3D Structures]] | |||
[[Category: | *[[Tubulin tyrosine ligase 3D structures|Tubulin tyrosine ligase 3D structures]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bos taurus]] | |||
[[Category: Gallus gallus]] | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Abel A-C]] | |||
[[Category: Alvarez-Bernad B]] | |||
[[Category: Boiarska Z]] | |||
[[Category: Bonato F]] | |||
[[Category: Diaz JF]] | |||
[[Category: Horvath D]] | |||
[[Category: Lucena-Agell D]] | |||
[[Category: Marzullo P]] | |||
[[Category: Passarella D]] | |||
[[Category: Perez-Pena H]] | |||
[[Category: Pieraccini S]] | |||
[[Category: Prota AE]] | |||
[[Category: Santini B]] | |||
[[Category: Sironi M]] | |||
[[Category: Steinmetz MO]] | |||
[[Category: Vasile F]] | |||
Latest revision as of 09:17, 4 March 2026
Tubulin - maytansinoid - 6 complex
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