8b7j: Difference between revisions
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==Human HSP90 alpha ATP Binding Domain, ATP-lid closed conformation, R46A== | |||
<StructureSection load='8b7j' size='340' side='right'caption='[[8b7j]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8b7j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B7J FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b7j OCA], [https://pdbe.org/8b7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b7j RCSB], [https://www.ebi.ac.uk/pdbsum/8b7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b7j ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: Frech | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Boisbouvier J]] | ||
[[Category: | [[Category: Brustcher B]] | ||
[[Category: Crublet E]] | |||
[[Category: Favier A]] | |||
[[Category: Frech M]] | |||
[[Category: Gans P]] | |||
[[Category: Henot F]] | |||
[[Category: Josso P]] | |||
[[Category: Loison C]] | |||
[[Category: Macek P]] | |||
[[Category: Rioual E]] | |||
Latest revision as of 06:26, 19 June 2024
Human HSP90 alpha ATP Binding Domain, ATP-lid closed conformation, R46A
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