8f4q: Difference between revisions
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New page: '''Unreleased structure''' The entry 8f4q is ON HOLD Authors: Liu, S. Description: rat branched chain ketoacid dehydrogenase kinase in complex with inhibtors [[Category: Unreleased Str... |
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==rat branched chain ketoacid dehydrogenase kinase in complex with inhibtors== | |||
<StructureSection load='8f4q' size='340' side='right'caption='[[8f4q]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8f4q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus Rattus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F4Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F4Q FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.151Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XER:6-chloranyl-2-fluoranyl-thieno[3,2-b]thiophene-5-carboxylic+acid'>XER</scene></td></tr> | ||
[[Category: Liu | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f4q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f4q OCA], [https://pdbe.org/8f4q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f4q RCSB], [https://www.ebi.ac.uk/pdbsum/8f4q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f4q ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/BCKD_RAT BCKD_RAT] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus]] | |||
[[Category: Liu S]] | |||
Latest revision as of 09:48, 4 March 2026
rat branched chain ketoacid dehydrogenase kinase in complex with inhibtors
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