8hgh: Difference between revisions
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New page: '''Unreleased structure''' The entry 8hgh is ON HOLD Authors: Zhong, Q.H., Chu, H.L., Wang, G.P., Zhang, C., Wei, Y., Qiao, J., Hang, J. Description: Structure of 2:2 PAPP-A/STC2 compl... |
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==Structure of 2:2 PAPP-A.STC2 complex== | |||
<StructureSection load='8hgh' size='340' side='right'caption='[[8hgh]], [[Resolution|resolution]] 4.16Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8hgh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HGH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HGH FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.16Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hgh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hgh OCA], [https://pdbe.org/8hgh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hgh RCSB], [https://www.ebi.ac.uk/pdbsum/8hgh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hgh ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Wang | [https://www.uniprot.org/uniprot/MALE_ECOLI MALE_ECOLI] Involved in the high-affinity maltose membrane transport system MalEFGK. Initial receptor for the active transport of and chemotaxis toward maltooligosaccharides.[https://www.uniprot.org/uniprot/PAPP1_HUMAN PAPP1_HUMAN] Metalloproteinase which specifically cleaves IGFBP-4 and IGFBP-5, resulting in release of bound IGF. Cleavage of IGFBP-4 is dramatically enhanced by the presence of IGF, whereas cleavage of IGFBP-5 is slightly inhibited by the presence of IGF.<ref>PMID:10077652</ref> <ref>PMID:10913121</ref> <ref>PMID:11522292</ref> | ||
[[Category: | == References == | ||
[[Category: | <references/> | ||
[[Category: Zhong | __TOC__ | ||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Chu HL]] | |||
[[Category: Hang J]] | |||
[[Category: Qiao J]] | |||
[[Category: Wang GP]] | |||
[[Category: Wei Y]] | |||
[[Category: Zhang C]] | |||
[[Category: Zhong QH]] | |||
Latest revision as of 09:54, 9 October 2024
Structure of 2:2 PAPP-A.STC2 complex
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