8f99: Difference between revisions
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New page: '''Unreleased structure''' The entry 8f99 is ON HOLD Authors: Fan, P., Zhao, Y., Renslo, A.R., Arkin, M.R. Description: Compound 10 bound to procaspase-6 [[Category: Unreleased Structu... |
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==Compound 10 bound to procaspase-6== | |||
<StructureSection load='8f99' size='340' side='right'caption='[[8f99]], [[Resolution|resolution]] 2.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8f99]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F99 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XMR:5-fluoro-2-({[(3M)-3-(1,3-oxazol-4-yl)pyridin-2-yl]amino}methyl)phenol'>XMR</scene></td></tr> | ||
[[Category: Arkin | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f99 OCA], [https://pdbe.org/8f99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f99 RCSB], [https://www.ebi.ac.uk/pdbsum/8f99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f99 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Renslo | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arkin MR]] | |||
[[Category: Fan P]] | |||
[[Category: Renslo AR]] | |||
[[Category: Zhao Y]] | |||
Latest revision as of 11:39, 13 December 2023
Compound 10 bound to procaspase-6
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