8fbv: Difference between revisions
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New page: '''Unreleased structure''' The entry 8fbv is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Compound 7 bound to procaspase-6== | |||
<StructureSection load='8fbv' size='340' side='right'caption='[[8fbv]], [[Resolution|resolution]] 2.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8fbv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8FBV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8FBV FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.86Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XOW:5-fluoro-2-({[(3M)-3-(1H-imidazol-2-yl)pyridin-2-yl]amino}methyl)phenol'>XOW</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8fbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8fbv OCA], [https://pdbe.org/8fbv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8fbv RCSB], [https://www.ebi.ac.uk/pdbsum/8fbv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8fbv ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CASP6_HUMAN CASP6_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Arkin MR]] | |||
[[Category: Fan P]] | |||
[[Category: Renslo AR]] | |||
[[Category: Zhao Y]] | |||
