4kzz: Difference between revisions

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<StructureSection load='4kzz' size='340' side='right'caption='[[4kzz]], [[Resolution|resolution]] 7.03&Aring;' scene=''>
<StructureSection load='4kzz' size='340' side='right'caption='[[4kzz]], [[Resolution|resolution]] 7.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4kzz]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KZZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[4kzz]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KZZ FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzz OCA], [https://pdbe.org/4kzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kzz RCSB], [https://www.ebi.ac.uk/pdbsum/4kzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kzz ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 7.0305&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kzz OCA], [https://pdbe.org/4kzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kzz RCSB], [https://www.ebi.ac.uk/pdbsum/4kzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kzz ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[https://www.uniprot.org/uniprot/G1TGI6_RABIT G1TGI6_RABIT] Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria. Acts as a PPP1R16B-dependent substrate of PPP1CA.[HAMAP-Rule:MF_03016]
[https://www.uniprot.org/uniprot/IF1AX_HUMAN IF1AX_HUMAN] Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
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<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Synthetic construct]]
[[Category: Lomakin IB]]
[[Category: Lomakin IB]]
[[Category: Steitz TA]]
[[Category: Steitz TA]]