8c4j: Difference between revisions

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New page: '''Unreleased structure''' The entry 8c4j is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 8c4j is ON HOLD
==CdaA-compound 4 complex==
 
<StructureSection load='8c4j' size='340' side='right'caption='[[8c4j]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8c4j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C4J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C4J FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=TI5:5-methylpyrimidin-4-amine'>TI5</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c4j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c4j OCA], [https://pdbe.org/8c4j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c4j RCSB], [https://www.ebi.ac.uk/pdbsum/8c4j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c4j ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DACA_LISMO DACA_LISMO] Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a signaling compound secreted into the host's cytosol where it triggers the cytosolic surveillance pathway (CSP), a host pathway of innate immunity characterized by expression of beta interferon (IFN-beta) and coregulated genes.<ref>PMID:20508090</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Listeria monocytogenes]]
[[Category: Ficner R]]
[[Category: Neumann P]]