8c4p: Difference between revisions

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'''Unreleased structure'''


The entry 8c4p is ON HOLD
==CdaA-compound 7 complex==
 
<StructureSection load='8c4p' size='340' side='right'caption='[[8c4p]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8c4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes Listeria monocytogenes]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8C4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8C4P FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=TJ9:~{N}-[5-(2-azanyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]ethanamide'>TJ9</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8c4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8c4p OCA], [https://pdbe.org/8c4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8c4p RCSB], [https://www.ebi.ac.uk/pdbsum/8c4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8c4p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DACA_LISMO DACA_LISMO] Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a signaling compound secreted into the host's cytosol where it triggers the cytosolic surveillance pathway (CSP), a host pathway of innate immunity characterized by expression of beta interferon (IFN-beta) and coregulated genes.<ref>PMID:20508090</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Listeria monocytogenes]]
[[Category: Ficner R]]
[[Category: Neumann P]]
Retrieved from "https://proteopedia.org/8c4p"