4o72: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4o72]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O72 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4o72]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O72 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4O72 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2R4:8-(DIBENZO[B,D]THIOPHEN-4-YL)-2-(MORPHOLIN-4-YL)-4H-CHROMEN-4-ONE'>2R4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2R4:8-(DIBENZO[B,D]THIOPHEN-4-YL)-2-(MORPHOLIN-4-YL)-4H-CHROMEN-4-ONE'>2R4</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o72 OCA], [https://pdbe.org/4o72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o72 RCSB], [https://www.ebi.ac.uk/pdbsum/4o72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o72 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4o72 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o72 OCA], [https://pdbe.org/4o72 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4o72 RCSB], [https://www.ebi.ac.uk/pdbsum/4o72 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4o72 ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 17:07, 20 September 2023

Crystal structure of the first bromodomain of human BRD4 in complex with NU7441

4o72, resolution 1.40Å

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