8i65: Difference between revisions
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New page: '''Unreleased structure''' The entry 8i65 is ON HOLD Authors: Raj, P., Paul, A., Gopal, B. Description: Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in comple... |
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==Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid), Form I== | |||
<StructureSection load='8i65' size='340' side='right'caption='[[8i65]], [[Resolution|resolution]] 1.72Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8i65]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I65 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.72Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CU:2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLIC+ACID'>5CU</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i65 OCA], [https://pdbe.org/8i65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i65 RCSB], [https://www.ebi.ac.uk/pdbsum/8i65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i65 ProSAT]</span></td></tr> | ||
[[Category: Gopal | </table> | ||
[[Category: Paul | == Function == | ||
[https://www.uniprot.org/uniprot/UNG_MYCTU UNG_MYCTU] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Gopal B]] | |||
[[Category: Paul A]] | |||
[[Category: Raj P]] | |||
Latest revision as of 07:25, 12 July 2023
Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with isoorotic acid (2,4-Dihydroxypyrimidine-5-carboxylic Acid), Form I
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