8i6d: Difference between revisions

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'''Unreleased structure'''


The entry 8i6d is ON HOLD
==Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Hydroxy-2,4(1H,3H)-pyrimidinedione, Form VI==
 
<StructureSection load='8i6d' size='340' side='right'caption='[[8i6d]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
Authors: Raj, P., Paul, A., Gopal, B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8i6d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I6D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I6D FirstGlance]. <br>
Description: Crystal structure of Mycobacterium tuberculosis Uracil-DNA glycosylase in complex with 5-Hydroxydihydro-2,4(1H,3H)-pyrimidinedione, Form VI
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ODF:5-oxidanyl-1~{H}-pyrimidine-2,4-dione'>ODF</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
[[Category: Raj, P]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i6d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i6d OCA], [https://pdbe.org/8i6d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i6d RCSB], [https://www.ebi.ac.uk/pdbsum/8i6d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i6d ProSAT]</span></td></tr>
[[Category: Gopal, B]]
</table>
[[Category: Paul, A]]
== Function ==
[https://www.uniprot.org/uniprot/UNG_MYCTU UNG_MYCTU] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Gopal B]]
[[Category: Paul A]]
[[Category: Raj P]]
Retrieved from "https://proteopedia.org/8i6d"