8g6j: Difference between revisions

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New page: '''Unreleased structure''' The entry 8g6j is ON HOLD Authors: Holm, M., Natchiar, K.S., Rundlet, E.J., Myasnikov, A.G., Altman, R.B., Blanchard, S.C. Description: mRNA decoding in huma...
 
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'''Unreleased structure'''


The entry 8g6j is ON HOLD
==mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)==
 
<StructureSection load='8g6j' size='340' side='right'caption='[[8g6j]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
Authors: Holm, M., Natchiar, K.S., Rundlet, E.J., Myasnikov, A.G., Altman, R.B., Blanchard, S.C.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8g6j]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G6J FirstGlance]. <br>
Description: mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1MA:6-HYDRO-1-METHYLADENOSINE-5-MONOPHOSPHATE'>1MA</scene>, <scene name='pdbligand=3HE:4-{(2R)-2-[(1S,3S,5S)-3,5-DIMETHYL-2-OXOCYCLOHEXYL]-2-HYDROXYETHYL}PIPERIDINE-2,6-DIONE'>3HE</scene>, <scene name='pdbligand=4AC:N(4)-ACETYLCYTIDINE-5-MONOPHOSPHATE'>4AC</scene>, <scene name='pdbligand=4SU:4-THIOURIDINE-5-MONOPHOSPHATE'>4SU</scene>, <scene name='pdbligand=5MC:5-METHYLCYTIDINE-5-MONOPHOSPHATE'>5MC</scene>, <scene name='pdbligand=6MZ:N6-METHYLADENOSINE-5-MONOPHOSPHATE'>6MZ</scene>, <scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=AME:N-ACETYLMETHIONINE'>AME</scene>, <scene name='pdbligand=B8N:(2~{R})-2-azanyl-4-[5-[(2~{S},3~{R},4~{S},5~{R})-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]-3-methyl-2,6-bis(oxidanylidene)pyrimidin-1-yl]butanoic+acid'>B8N</scene>, <scene name='pdbligand=G7M:N7-METHYL-GUANOSINE-5-MONOPHOSPHATE'>G7M</scene>, <scene name='pdbligand=GSP:5-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=H2U:5,6-DIHYDROURIDINE-5-MONOPHOSPHATE'>H2U</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=HMT:(3BETA)-O~3~-[(2R)-2,6-DIHYDROXY-2-(2-METHOXY-2-OXOETHYL)-6-METHYLHEPTANOYL]CEPHALOTAXINE'>HMT</scene>, <scene name='pdbligand=HY3:3-HYDROXYPROLINE'>HY3</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=M3L:N-TRIMETHYLLYSINE'>M3L</scene>, <scene name='pdbligand=MA6:6N-DIMETHYLADENOSINE-5-MONOPHOSHATE'>MA6</scene>, <scene name='pdbligand=MET:METHIONINE'>MET</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MIA:2-METHYLTHIO-N6-ISOPENTENYL-ADENOSINE-5-MONOPHOSPHATE'>MIA</scene>, <scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene>, <scene name='pdbligand=OMC:O2-METHYLYCYTIDINE-5-MONOPHOSPHATE'>OMC</scene>, <scene name='pdbligand=OMG:O2-METHYLGUANOSINE-5-MONOPHOSPHATE'>OMG</scene>, <scene name='pdbligand=OMU:O2-METHYLURIDINE+5-MONOPHOSPHATE'>OMU</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene>, <scene name='pdbligand=PSU:PSEUDOURIDINE-5-MONOPHOSPHATE'>PSU</scene>, <scene name='pdbligand=PUT:1,4-DIAMINOBUTANE'>PUT</scene>, <scene name='pdbligand=SAC:N-ACETYL-SERINE'>SAC</scene>, <scene name='pdbligand=SPD:SPERMIDINE'>SPD</scene>, <scene name='pdbligand=UR3:3-METHYLURIDINE-5-MONOPHOSHATE'>UR3</scene>, <scene name='pdbligand=UY1:[(2~{R},3~{R},4~{R},5~{S})-5-[2,4-bis(oxidanylidene)-1~{H}-pyrimidin-5-yl]-4-methoxy-3-oxidanyl-oxolan-2-yl]methyl+dihydrogen+phosphate'>UY1</scene>, <scene name='pdbligand=V5N:(2~{S},3~{S})-2-azanyl-3-(1~{H}-imidazol-5-yl)-3-oxidanyl-propanoic+acid'>V5N</scene>, <scene name='pdbligand=YRB:(3~{S},6~{S},9~{S},12~{S},15~{R},18~{R},21~{R})-15-[(2~{S})-butan-2-yl]-3,4,10,12,13-pentamethyl-6-[(2~{S})-2-methylbutyl]-9,18-bis[(1~{R})-2-methyl-1-oxidanyl-propyl]-1,4,7,10,13,16,19-heptazabicyclo[19.4.0]pentacosane-2,5,8,11,14,17,20-heptone'>YRB</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Myasnikov, A.G]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g6j OCA], [https://pdbe.org/8g6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g6j RCSB], [https://www.ebi.ac.uk/pdbsum/8g6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g6j ProSAT]</span></td></tr>
[[Category: Blanchard, S.C]]
</table>
[[Category: Natchiar, K.S]]
== Function ==
[[Category: Altman, R.B]]
[https://www.uniprot.org/uniprot/RL28_HUMAN RL28_HUMAN]
[[Category: Holm, M]]
__TOC__
[[Category: Rundlet, E.J]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Altman RB]]
[[Category: Blanchard SC]]
[[Category: Holm M]]
[[Category: Myasnikov AG]]
[[Category: Natchiar KS]]
[[Category: Rundlet EJ]]

Latest revision as of 13:54, 1 July 2026

mRNA decoding in human is kinetically and structurally distinct from bacteria (GA state 2)

8g6j, resolution 2.80Å

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