7fv8: Difference between revisions

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'''Unreleased structure'''


The entry 7fv8 is ON HOLD
==PanDDA analysis group deposition -- PHIP in complex with Z964297186==
 
<StructureSection load='7fv8' size='340' side='right'caption='[[7fv8]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
Authors: Grosjean, H., Tomlinson, C., Bradshaw, W.J., Koekemoer, L., Krojer, T., Fearon, D., Biggin, P.C., von Delft, F.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7fv8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FV8 FirstGlance]. <br>
Description: PanDDA analysis group deposition --PHIP in complex with Z964297186
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZL8:4-(3-chlorobenzoyl)-N-[3-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-3-oxopropyl]-1,4-diazepane-1-carboxamide'>ZL8</scene></td></tr>
[[Category: Fearon, D]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fv8 OCA], [https://pdbe.org/7fv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fv8 RCSB], [https://www.ebi.ac.uk/pdbsum/7fv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fv8 ProSAT]</span></td></tr>
[[Category: Grosjean, H]]
</table>
[[Category: Krojer, T]]
== Function ==
[[Category: Biggin, P.C]]
[https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref>
[[Category: Von Delft, F]]
== References ==
[[Category: Koekemoer, L]]
<references/>
[[Category: Bradshaw, W.J]]
__TOC__
[[Category: Tomlinson, C]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Biggin PC]]
[[Category: Bradshaw WJ]]
[[Category: Fearon D]]
[[Category: Grosjean H]]
[[Category: Koekemoer L]]
[[Category: Krojer T]]
[[Category: Tomlinson C]]
[[Category: Von Delft F]]
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