7fvb: Difference between revisions
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==PanDDA analysis group deposition -- PHIP in complex with Z6617539657== | |||
<StructureSection load='7fvb' size='340' side='right'caption='[[7fvb]], [[Resolution|resolution]] 1.38Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7fvb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FVB FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.38Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZLW:N-(2-aminoethyl)-4-(furan-2-carbonyl)piperazine-1-carboxamide'>ZLW</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fvb OCA], [https://pdbe.org/7fvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fvb RCSB], [https://www.ebi.ac.uk/pdbsum/7fvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fvb ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/PHIP_HUMAN PHIP_HUMAN] Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:12242307</ref> <ref>PMID:21834987</ref> | ||
[[Category: | == References == | ||
[[Category: Koekemoer | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: Tomlinson | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Biggin PC]] | |||
[[Category: Bradshaw WJ]] | |||
[[Category: Fearon D]] | |||
[[Category: Grosjean H]] | |||
[[Category: Koekemoer L]] | |||
[[Category: Krojer T]] | |||
[[Category: Tomlinson C]] | |||
[[Category: Von Delft F]] | |||
Latest revision as of 15:08, 18 February 2026
PanDDA analysis group deposition -- PHIP in complex with Z6617539657
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