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| [[Image:1k6f.jpg|left|200px]]
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| <!--
| | ==Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3== |
| The line below this paragraph, containing "STRUCTURE_1k6f", creates the "Structure Box" on the page.
| | <StructureSection load='1k6f' size='340' side='right'caption='[[1k6f]], [[Resolution|resolution]] 1.30Å' scene=''> |
| You may change the PDB parameter (which sets the PDB file loaded into the applet)
| | == Structural highlights == |
| or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
| | <table><tr><td colspan='2'>[[1k6f]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saimiriine_gammaherpesvirus_2 Saimiriine gammaherpesvirus 2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K6F FirstGlance]. <br> |
| or leave the SCENE parameter empty for the default display.
| | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3Å</td></tr> |
| --> | | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6f OCA], [https://pdbe.org/1k6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k6f RCSB], [https://www.ebi.ac.uk/pdbsum/1k6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6f ProSAT]</span></td></tr> |
| {{STRUCTURE_1k6f| PDB=1k6f | SCENE= }}
| | </table> |
| | == Function == |
| | [https://www.uniprot.org/uniprot/Q80BK4_SHV2 Q80BK4_SHV2] |
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| '''Crystal Structure of the Collagen Triple Helix Model [(Pro-Pro-Gly)10]3'''
| | ==See Also== |
| | | *[[Collagen 3D structures|Collagen 3D structures]] |
| | | __TOC__ |
| ==Overview== | | </StructureSection> |
| The first report of the full-length structure of the collagen-like polypeptide [(Pro-Pro-Gly)(10)](3) is given. This structure was obtained from crystals grown in a microgravity environment, which diffracted up to 1.3 A, using synchrotron radiation. The final model, which was refined to an R(factor) of 0.18, is the highest-resolution description of a collagen triple helix reported to date. This structure provides clues regarding a series of aspects related to collagen triple helix structure and assembly. The strict dependence of proline puckering on the position inside the Pro-Pro-Gly triplets and the correlation between backbone and side chain dihedral angles support the propensity-based mechanism of triple helix stabilization/destabilization induced by hydroxyproline. Furthermore, the analysis of [(Pro-Pro-Gly)(10)](3) packing, which is governed by electrostatic interactions, suggests that charges may act as locking features in the axial organization of triple helices in the collagen fibrils.
| | [[Category: Large Structures]] |
| | | [[Category: Saimiriine gammaherpesvirus 2]] |
| ==About this Structure==
| | [[Category: Berisio R]] |
| Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6F OCA].
| | [[Category: Mazzarella L]] |
| | | [[Category: Vitagliano L]] |
| ==Reference==
| | [[Category: Zagari A]] |
| Crystal structure of the collagen triple helix model [(Pro-Pro-Gly)(10)](3)., Berisio R, Vitagliano L, Mazzarella L, Zagari A, Protein Sci. 2002 Feb;11(2):262-70. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11790836 11790836]
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| [[Category: Berisio, R.]] | |
| [[Category: Mazzarella, L.]] | |
| [[Category: Vitagliano, L.]] | |
| [[Category: Zagari, A]] | |
| [[Category: Amino acid preference]]
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| [[Category: Collagen stability]]
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| [[Category: Puckering]]
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| [[Category: Triple helix]]
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| ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 22:21:44 2008''
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