8gcl: Difference between revisions
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==Cryo-EM structure of hAQP2 in DDM== | |||
<StructureSection load='8gcl' size='340' side='right'caption='[[8gcl]], [[Resolution|resolution]] 2.89Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8gcl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GCL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GCL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.89Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8gcl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8gcl OCA], [https://pdbe.org/8gcl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8gcl RCSB], [https://www.ebi.ac.uk/pdbsum/8gcl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8gcl ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Disease == | ||
[[Category: | [https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry. | ||
[[Category: Numoto | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/AQP2_HUMAN AQP2_HUMAN] Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. | ||
[[Category: Suzuki | __TOC__ | ||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fujiyoshi Y]] | |||
[[Category: Kamegawa A]] | |||
[[Category: Nishikawa K]] | |||
[[Category: Numoto N]] | |||
[[Category: Suzuki H]] | |||
[[Category: Suzuki S]] | |||