7xvk: Difference between revisions
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==Modularity of Phytophthora effectors enables host mimicry of a principal phosphatase== | |||
<StructureSection load='7xvk' size='340' side='right'caption='[[7xvk]], [[Resolution|resolution]] 2.29Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7xvk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Phytophthora_sojae Phytophthora sojae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XVK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xvk OCA], [https://pdbe.org/7xvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xvk RCSB], [https://www.ebi.ac.uk/pdbsum/7xvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xvk ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/2AAB_ARATH 2AAB_ARATH] The A subunit of protein phosphatase 2A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. Involved during developmental process such as seedling and floral developments. Seems to act as a negative regulator of PP2A catalytic activity. Associates with the serine/threonine-protein phosphatase PP2A catalytic subunit C and regulatory subunit B' to positively regulates beta-oxidation of fatty acids and protoauxins in peroxisomes by dephosphorylating peroxisomal beta-oxidation-related proteins (PubMed:25489022).<ref>PMID:14973165</ref> <ref>PMID:25489022</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Phytophthora sojae]] | |||
[[Category: Wang J]] | |||
[[Category: Wang Y]] | |||