Budesonide: Difference between revisions
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<StructureSection load='' size='340' side='right' caption=' | <StructureSection load='' size='340' side='right' caption='Budesonide' scene='96/962959/Cv/1'> | ||
Budesonide, sold under the brand name Pulmicort among others, is a medication of the corticosteroid type. | Budesonide, sold under the brand name Pulmicort among others, is a medication of the corticosteroid type. It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms. The inhaled form is used in the long-term management of asthma and chronic obstructive pulmonary disease (COPD). The nasal spray is used for allergic rhinitis and nasal polyps. The pills in a delayed release form and rectal forms may be used for inflammatory bowel disease including Crohn's disease, ulcerative colitis, and microscopic colitis. See also [https://en.wikipedia.org/wiki/Budesonide Budesonide]. | ||
Budesonide is an agonist of [[glucocorticoid receptors]]. Among its effects are: | |||
*Controls the rate of protein synthesis. | |||
*Depresses the migration of polymorphonuclear leukocytes and fibroblasts. | |||
*Reverses capillary permeability and lysosomal stabilization at the cellular level to prevent or control inflammation. | |||
*Has a potent glucocorticoid activity and weak [[mineralocorticoid]] activity. | |||
<scene name='96/962959/Tert/1'>Glucocorticoid Receptor in complex with budesonide</scene> ([[5nfp]]). | <scene name='96/962959/Tert/1'>Glucocorticoid Receptor in complex with budesonide</scene> ([[5nfp]]). | ||
<scene name='96/962959/Binding_site/1'>Budesonide binding site</scene>. Water molecule is shown as red sphere. | |||
</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
<references/> | <references/> | ||
