7g1b: Difference between revisions

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'''Unreleased structure'''


The entry 7g1b is ON HOLD
==Crystal Structure of human FABP4 in complex with 2-[1-[(3-chlorophenyl)methyl]indol-2-yl]cyclopropane-1-carboxylic acid, i.e. SMILES C1(=Cc2c(N1Cc1cc(ccc1)Cl)cccc2)[C@H]1[C@@H](C1)C(=O)O with IC50=0.155 microM==
 
<StructureSection load='7g1b' size='340' side='right'caption='[[7g1b]], [[Resolution|resolution]] 1.17&Aring;' scene=''>
Authors: Ehler, A., Benz, J., Obst, U., Rudolph, M.G.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[7g1b]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G1B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G1B FirstGlance]. <br>
Description: Crystal Structure of human FABP4 in complex with 2-[1-[(3-chlorophenyl)methyl]indol-2-yl]cyclopropane-1-carboxylic acid
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.17&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=WNB:(1S,2S)-2-{1-[(3-chlorophenyl)methyl]-1H-indol-2-yl}cyclopropane-1-carboxylic+acid'>WNB</scene></td></tr>
[[Category: Ehler, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g1b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g1b OCA], [https://pdbe.org/7g1b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g1b RCSB], [https://www.ebi.ac.uk/pdbsum/7g1b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g1b ProSAT]</span></td></tr>
[[Category: Benz, J]]
</table>
[[Category: Obst, U]]
== Function ==
[[Category: Rudolph, M.G]]
[https://www.uniprot.org/uniprot/FABP4_HUMAN FABP4_HUMAN] Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus (By similarity).
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Benz J]]
[[Category: Ehler A]]
[[Category: Obst U]]
[[Category: Rudolph MG]]
Retrieved from "https://proteopedia.org/7g1b"