7g1q: Difference between revisions
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New page: '''Unreleased structure''' The entry 7g1q is ON HOLD Authors: Ehler, A., Benz, J., Obst, U., Rudolph, M.G. Description: Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-c... |
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==Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid== | |||
<StructureSection load='7g1q' size='340' side='right'caption='[[7g1q]], [[Resolution|resolution]] 1.24Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[7g1q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7G1Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7G1Q FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.24Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=IOV:(1~{R},2~{S})-2-[(5-aminocarbonyl-3-ethoxycarbonyl-4-methyl-thiophen-2-yl)carbamoyl]cyclohexane-1-carboxylic+acid'>IOV</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7g1q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7g1q OCA], [https://pdbe.org/7g1q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7g1q RCSB], [https://www.ebi.ac.uk/pdbsum/7g1q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7g1q ProSAT]</span></td></tr> | ||
[[Category: Benz | </table> | ||
[[Category: Obst | == Function == | ||
[[Category: Rudolph | [https://www.uniprot.org/uniprot/FABP5_HUMAN FABP5_HUMAN] High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Benz J]] | |||
[[Category: Ehler A]] | |||
[[Category: Obst U]] | |||
[[Category: Rudolph MG]] | |||
Latest revision as of 09:25, 9 October 2024
Crystal Structure of human FABP5 in complex with (1S,2R)-2-[(5-carbamoyl-3-ethoxycarbonyl-4-methyl-2-thienyl)carbamoyl]cyclohexanecarboxylic acid
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