8ow4: Difference between revisions

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'''Unreleased structure'''


The entry 8ow4 is ON HOLD
==2.75 angstrom crystal structure of human NFAT1 with bound DNA==
 
<StructureSection load='8ow4' size='340' side='right'caption='[[8ow4]], [[Resolution|resolution]] 2.75&Aring;' scene=''>
Authors: Lopez-Sagaseta, J., Erausquin, E., Hernandez-Morales, S., Urdiciain, A., Lasarte, J.J., Lozano, T.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8ow4]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OW4 FirstGlance]. <br>
Description: 2.75 angstrom crystal structure of human NFAT1 with bound DNA
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.75&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ow4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ow4 OCA], [https://pdbe.org/8ow4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ow4 RCSB], [https://www.ebi.ac.uk/pdbsum/8ow4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ow4 ProSAT]</span></td></tr>
[[Category: Erausquin, E]]
</table>
[[Category: Lopez-Sagaseta, J]]
== Function ==
[[Category: Urdiciain, A]]
[https://www.uniprot.org/uniprot/NFAC2_HUMAN NFAC2_HUMAN] Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.<ref>PMID:21871017</ref>
[[Category: Lozano, T]]
== References ==
[[Category: Lasarte, J.J]]
<references/>
[[Category: Hernandez-Morales, S]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Erausquin E]]
[[Category: Hernandez-Morales S]]
[[Category: Lasarte JJ]]
[[Category: Lopez-Sagaseta J]]
[[Category: Lozano T]]
[[Category: Urdiciain A]]